The fate of high redshift massive compact galaxies in dense environments

Massive compact galaxies seem to be more common at high redshift than in the local universe, especially in denser environments. To investigate the fate of such massive galaxies identified at z~2 we analyse the evolution of their properties in three cosmological hydrodynamical simulations that form virialised galaxy groups of mass ~10^13 Msun hosting a central massive elliptical/S0 galaxy by redshift zero. We find that at redshift ~2 the population of galaxies with M_*> 2 10^10 Msun is diverse in terms of mass, velocity dispersion, star formation and effective radius, containing both very compact and relatively extended objects. In each simulation all the compact satellite galaxies have merged into the central galaxy by redshift 0 (with the exception of one simulation where one of such satellite galaxy survives). Satellites of similar mass at z = 0 are all less compact than their high redshift counterparts. They form later than the galaxies in the z = 2 sample and enter the group potential at z < 1, when dynamical friction times are longer than the Hubble time. Also, by z = 0 the central galaxies have increased substantially their characteristic radius via a combination of in situ star formation and mergers. Hence in a group environment descendants of compact galaxies either evolve towards larger sizes or they disappear before the present time as a result of the environment in which they evolve. Since the group-sized halos that we consider are representative of dense environments in the LambdaCDM cosmology, we conclude that the majority of high redshift compact massive galaxies do not survive until today as a result of the environment.Comment: 10 pages, 4 figures, submitted to MNRA

Precision Measurement of a Particle Mass at the Linear Collider

Precision measurement of the stop mass at the ILC is done in a method based on cross-sections measurements at two different center-of-mass energies. This allows to minimize both the statistical and systematic errors. In the framework of the MSSM, a light stop, compatible with electro-weak baryogenesis, is studied in its decay into a charm jet and neutralino, the Lightest Supersymmetric Particle(LSP), as a candidate of dark matter. This takes place for a small stop-neutralino mass difference.Comment: 6 pages, 4 figures, 3tables, Conference(Workshop)-LCWS/ILC2007-June,2,200

A Method for the Precision Mass Measurement of the Stop Quark at the International Linear Collider

Many supersymmetric models predict new particles within the reach of the next generation of colliders. For an understanding of the model structure and the mechanism(s) of symmetry breaking, it is important to know the masses of the new particles precisely. In this article the measurement of the mass of the scalar partner of the top quark (stop) at an e+e- collider is studied. A relatively light stop is motivated by attempts to explain electroweak baryogenesis and can play an important role in dark matter relic density. A method is presented which makes use of cross-section measurements near the pair-production threshold as well as at higher center-of-mass energies. It is shown that this method not only increases the statistical precision, but also greatly reduces the systematic uncertainties, which can be important. Numerical results are presented, based on a realistic event simulation, for two signal selection strategies: using conventional selection cuts, and using an Iterative Discriminant Analysis (IDA). Our studies indicate that a precision of \Delta\mstop = 0.42 GeV can be achieved, representing a major improvement over previous studies. While the analysis of stops is particularly challenging due to the possibility of stop hadronization, the general procedure could be applied to the mass measurement of other particles as well. We also comment on the potential of the IDA to discover a stop quark in this scenario, and we revisit the accuracy of the theoretical predictions for the neutralino relic densityComment: 41 pages, 14 figures, in JHEP forma

Two-Loop QCD Corrections to the Heavy-to-Light Quark Decay

We present an analytic expression for the two-loop QCD corrections to the decay process b -> u W^*, where b and u are a massive and massless quark, respectively, while W^* is an off-shell charged weak boson. Since the W-boson can subsequently decay in a lepton anti-neutrino pair, the results of this paper are a first step towards a fully analytic computation of differential distributions for the semileptonic decay of a b-quark. The latter partonic process plays a crucial role in the study of inclusive semileptonic charmless decays of B-mesons. The three independent form factors characterizing the b W u vertex are provided in form of a Laurent series in (d-4), where d is the space-time dimension. The coefficients in the series are expressed in terms of Harmonic Polylogarithms of maximal weight 4, and are functions of the invariant mass of the leptonic decay products of the W-boson.Comment: 27 pages, 3 figures, References added, version published on JHE

Report of the 2005 Snowmass Top/QCD Working Group

This report discusses several topics in both top quark physics and QCD at an International Linear Collider (ILC). Issues such as measurements at the $t\bar{t}$ threshold, including both theoretical and machine requirements, and the determination of electroweak top quark couplings, are reviewed. New results concerning the potential of a 500 GeV $e^+e^-$ collider for measuring $Wtb$ couplings and the top quark Yukawa coupling are presented. The status of higher order QCD corrections to jet production cross sections, heavy quark form factors, and longitudinal gauge boson scattering, needed for percent-level studies at the ILC, are reviewed. A new study of the measurement of the hadronic structure of the photon at a $\gamma\gamma$ collider is presented. The effects on top quark properties from several models of new physics, including composite models, Little Higgs theories, and CPT violation, are studied.Comment: 39 pages, many figs; typos fixed and refs added. Contributed to the 2005 International Linear Collider Physics and Detector Workshop and 2nd ILC Accelerator Workshop, Snowmass, Colorado, 14-27 Aug 200

Rhapsody. II. Subhalo Properties and the Impact of Tidal Stripping From a Statistical Sample of Cluster-Size Halos

We discuss the properties of subhalos in cluster-size halos, using a high-resolution statistical sample: the Rhapsody simulations introduced in Wu et al. (2012). We demonstrate that the criteria applied to select subhalos have significant impact on the inferred properties of the sample, including the scatter in the number of subhalos, the correlation between the subhalo number and formation time, and the shape of subhalos' spatial distribution and velocity structure. We find that the number of subhalos, when selected using the peak maximum circular velocity in their histories (a property expected to be closely related to the galaxy luminosity), is uncorrelated with the formation time of the main halo. This is in contrast to the previously reported correlation from studies where subhalos are selected by the current maximum circular velocity; we show that this difference is a result of the tidal stripping of the subhalos. We also find that the dominance of the main halo and the subhalo mass fraction are strongly correlated with halo concentration and formation history. These correlations are important to take into account when interpreting results from cluster samples selected with different criteria. Our sample also includes a fossil cluster, which is presented separately and placed in the context of the rest of the sample.Comment: 15 pages, 10 figures; Paper I: arXiv:1209.3309; replaced to match published versio

Computing for Perturbative QCD - A Snowmass White Paper

We present a study on high-performance computing and large-scale distributed computing for perturbative QCD calculations.Comment: 21 pages, 5 table

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.

Integrated approaches using different in vitro methods in combination with bioinformatics can (i) increase the success rate and speed of drug development; (ii) improve the accuracy of toxicological risk assessment; and (iii) increase our understanding of disease. Three-dimensional (3D) cell culture models are important building blocks of this strategy which has emerged during the last years. The majority of these models are organotypic, i.e., they aim to reproduce major functions of an organ or organ system. This implies in many cases that more than one cell type forms the 3D structure, and often matrix elements play an important role. This review summarizes the state of the art concerning commonalities of the different models. For instance, the theory of mass transport/metabolite exchange in 3D systems and the special analytical requirements for test endpoints in organotypic cultures are discussed in detail. In the next part, 3D model systems for selected organs--liver, lung, skin, brain--are presented and characterized in dedicated chapters. Also, 3D approaches to the modeling of tumors are presented and discussed. All chapters give a historical background, illustrate the large variety of approaches, and highlight up- and downsides as well as specific requirements. Moreover, they refer to the application in disease modeling, drug discovery and safety assessment. Finally, consensus recommendations indicate a roadmap for the successful implementation of 3D models in routine screening. It is expected that the use of such models will accelerate progress by reducing error rates and wrong predictions from compound testing

Does psychopathology at admission predict the length of inpatient stay in psychiatry? Implications for financing psychiatric services

Background: The debate on appropriate financing systems in inpatient psychiatry is ongoing. In this context, it is important to control resource use in terms of length of stay (LOS), which is the most costly factor in inpatient care and the one that can be influenced most easily. Previous studies have shown that psychiatric diagnoses provide only limited justification for explaining variation in LOS, and it has been suggested that measures such as psychopathology might be more appropriate to predict resource use. Therefore, we investigated the relationship between LOS and psychopathological syndromes or symptoms at admission as well as other characteristics such as sociodemographic and clinical variables. Methods: We considered routine medical data of patients admitted to the Psychiatric University Hospital Zurich in the years 2008 and 2009. Complete data on psychopathology at hospital admission were available in 3,220 inpatient episodes. A subsample of 2,939 inpatient episodes was considered in final statistical models, including psychopathology as well as complete datasets of further measures (e.g. sociodemographic, clinical, treatment-related and psychosocial variables). We used multivariate linear as well as logistic regression analysis with forward selection procedure to determine the predictors of LOS. Results: All but two syndrome scores (mania, hostility) were positively related to the length of stay. Final statistical models showed that syndromes or symptoms explained about 5% of the variation in length of stay. The inclusion of syndromes or symptoms as well as basic treatment variables and other factors led to an explained variation of up to 25%. Conclusions: Psychopathological syndromes and symptoms at admission and further characteristics only explained a small proportion of the length of inpatient stay. Thus, according to our sample, psychopathology might not be suitable as a primary indicator for estimating LOS and contingent costs. This might be considered in the development of future costing systems in psychiatry